Article Types
The Journal of Disease Mechanisms and Genomics welcomes a broad spectrum of scholarly contributions that advance the understanding of molecular, cellular, genetic, epigenetic, and translational mechanisms underlying human disease. Manuscripts should demonstrate scientific rigor and relevance to disease biology, precision medicine, or genomic sciences. The journal currently accepts the following article categories.
Original Research Articles
Original Research Articles constitute comprehensive reports of novel experimental, translational, computational, or clinical investigations. These submissions should present previously unpublished findings that substantially advance current understanding within biomedical and genomic sciences. Manuscripts should include a clearly defined hypothesis, methodology, appropriate statistical analyses, and a balanced interpretation of the findings.
Review Articles
Review Articles provide comprehensive, scholarly, and critical evaluations of existing literature within a defined area of biomedical, molecular, or genomic research. These articles are intended to synthesize current knowledge, identify conceptual and methodological gaps, discuss ongoing controversies, and propose future directions for investigation and translational development. Submissions should demonstrate intellectual depth, analytical rigor, and balanced interpretation of published evidence rather than merely summarizing previous studies.
Systematic Reviews
Systematic Reviews are structured evidence-based investigations that employ predefined methodologies to identify, evaluate, and synthesize relevant studies addressing a specific scientific or clinical question. Authors are strongly encouraged to follow internationally recognized reporting standards, such as PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and Cochrane methodological recommendations, where applicable.
Meta-Analyses
Meta-Analyses involve the quantitative statistical integration of findings from multiple independent studies to derive pooled estimates, strengthen evidence synthesis, and improve statistical power. Appropriate graphical presentations, such as forest plots, funnel plots, and subgroup analyses, are encouraged when relevant. Meta-Analyses should preferably follow PRISMA guidelines and accepted statistical reporting standards.
Short Communications
Short Communications are concise reports describing novel preliminary findings, innovative observations, or narrowly focused investigations that possess immediate scientific relevance and merit rapid dissemination. Short Communications should maintain the same scientific rigor and ethical standards expected of full-length research articles.
Brief Reports
Brief Reports are condensed original research articles presenting smaller datasets, focused experimental findings, pilot investigations, or targeted analyses of limited but scientifically valuable scope. Although shorter in format, brief Reports must provide sufficient methodological detail, appropriate statistical analyses, and scientifically meaningful conclusions.
Case Reports
Case Reports describe unique, rare, or clinically significant patient cases that contribute meaningful insights into disease mechanisms, diagnosis, therapeutic responses, genomic findings, or unusual clinical presentations. Case Reports should provide educational and scientific value beyond routine clinical description and should include appropriate patient consent and ethical considerations.
