About the Journal

The Journal of Disease Mechanisms and Genomics (JDMG) is an international, peer-reviewed scientific journal dedicated to advancing a deep, mechanistic understanding of human diseases through genomic, molecular, and systems-level research. The journal provides a focused platform for studies that elucidate how genetic variation, epigenetic regulation, molecular pathways, and gene–environment interactions drive disease initiation, progression, and therapeutic response.

JDMG is founded on the principle that precise characterization of disease mechanisms is essential for the development of predictive diagnostics, targeted therapies, and precision medicine. By integrating genomics with experimental biology, computational approaches, and clinical insights, the journal aims to bridge fundamental discovery with translational and clinical relevance.

Aims and Scope

The primary aim of JDMG is to publish high-quality research that reveals the molecular, cellular, and genomic bases of disease. The journal emphasizes mechanistic depth, methodological rigor, and biological significance.

JDMG welcomes contributions that:

  • Dissect disease pathways at genetic, epigenetic, transcriptomic, proteomic, and metabolomic levels
  • Identify causal mechanisms linking genomic variation to pathological phenotypes
  • Integrate multi-omics data to explain disease complexity and heterogeneity
  • Advance mechanistic insights that inform diagnosis, prognosis, and therapeutic strategies

Scope includes, but is not limited to:

  • Genetic and genomic mechanisms of disease
  • Functional genomics and gene regulation
  • Epigenetics and chromatin biology in disease
  • Transcriptomics and RNA biology
  • Proteomics and post-translational regulation
  • Metabolic dysregulation and disease pathways
  • Cancer genomics and tumor biology
  • Immunogenomics and inflammatory diseases
  • Neurogenomics and neurodegenerative disorders
  • Cardiovascular, metabolic, and endocrine diseases
  • Infectious disease genomics and host–pathogen interactions
  • Rare and inherited disorders
  • Systems biology and network medicine
  • Single-cell and spatial genomics
  • Gene–environment interactions
  • Precision and genomic medicine

Article Types

The Journal of Disease Mechanisms and Genomics publishes the following article categories:

  • Original Research Articles
  • Mechanistic Studies
  • Genomics and Multi-Omics Analyses
  • Review Articles (meta-analysis, systematic, scoping, and narrative)
  • Short Reports and Brief Communications
  • Methods and Technical Advances
  • Clinical Genomics and Translational Studies
  • Perspectives and Hypotheses
  • Data Resources and Bioinformatic Tools
  • Special Issue Articles